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IMPEL®

Multifrequency electrical impedance diagnostics for the ocular surface.

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IMPEL diagnostic device

IMPEL®

A technology platform combining ultra-high sensitivity bioelectrical sensing with artificial intelligence, developed to transform ophthalmic diagnosis from the ocular surface.

Tissue has an electrical signature.

All biological tissues have unique electrical properties that reflect their physiological state. IMPEL applies an imperceptible current and measures how the tissue responds across more than 60,000 frequencies per second.

The result is a unique electrical signature that artificial intelligence interprets to classify the state of the tissue.

The information is already in the tissue. Machine learning does not create it — it interprets it.

Cornea electrical signature visualization

Architecture optimized
for clinical sensitivity

Three elements that make the device a precision diagnostic tool.

Microcontact sensor

Miniaturized electrode designed for controlled contact with the ocular surface. No biological sample collection required.

500 Hz – 64 kHz

Multifrequency measurement

Sweep from 500 Hz to 64 kHz. Each frequency reveals a different tissue layer; together they build a complete electrical signature.

HEALTHY PATHOLOGICAL

AI classification

Supervised models with cross-validation interpret the tissue signature and return a diagnostic result in under one second.

IMPEL hardware device

Hardware designed
for the clinic.

A portable, self-contained, and simple-to-use device. Sub-second acquisition, touchscreen interface, and direct sensor connection.

Designed to integrate into clinical workflow without specialized training: the physician triggers the measurement, the system returns the result.

One device.
Multiple diagnostics.

IMPEL is not a single-indication product. It is a bioelectrical sensing platform that, through different classification algorithms, applies to multiple ocular surface pathologies on the same hardware.

APPLICATION 01

Dry Eye Disease

First clinical indication of the device. Objective detection and characterization of dry eye disease from the ocular surface electrical signature.

APPLICATION 02

Early Ocular Pemphigoid

Identification of pemphigoid in early stages, when physiological changes are not yet clinically evident. Preliminary results in 44 eyes.

APPLICATION 03

Corneal Characterization

Differentiation of corneal structural states — keratoconus, post-keratoplasty, healthy corneas — through multifrequency electrical signature.

APPLICATION 04

Tear Osmolarity

Osmolarity estimation with superior linearity and precision compared to existing commercial systems, in a physiological range relevant for dry eye diagnosis.

Scientific publications

The device and its applications were presented in four posters at the 2026 annual meeting of the Association for Research in Vision and Ophthalmology (ARVO), in collaboration with Buenos Aires Macula, Fundación Retina, Instituto Balseiro, and ROMAT Creator Center.

POSTER 5462

Device development and proof of concept

Characterization of the second-generation system through simulations, laboratory phantoms, and exploratory measurements in healthy and pathological subjects.

View poster →
POSTER 5463

Ocular pemphigoid: in-vivo pilot evaluation

44 eyes evaluated — 28 healthy controls and 16 patients with biopsy-confirmed pemphigoid. Discriminant component with robust separation between groups.

View poster →
POSTER 5469

Electrical profiling in keratoconus and post-keratoplasty

Phase-space representation of normalized capacitance and resistance. Distinctive patterns according to corneal structural state.

View poster →
POSTER 5411

Osmolarity evaluation vs. commercial device

Controlled experimental osmolarity model. IMPEL shows superior linearity and lower dispersion compared to the current commercial standard.

View poster →

Project status

Validated technology, granted patent, regulatory in progress.

US 12,402,801 B2
Granted patent

Hardware and measurement method — United States

4
ARVO 2026 publications

Four posters presented with preliminary results

10
Gen-2 prototypes built

Operational hardware, optimized shielding, clinic-ready

FDA 510(k)
Regulatory process initiated

Path to US clearance underway

Let's talk.

We welcome conversations with investors, strategic partners, clinical institutions, and ophthalmology professionals interested in the project.

CEO & CO-FOUNDER

Valentín Saravia

BAMtech Devices

EMAIL vsaravia@bamtechdevices.com PHONE +54 11 3399 5123